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A condition in which a newborn has hard, thick skin in diamond patterns.

Harlequin ichthyosis is a condition in which a newborn has hard, thick skin in diamond patterns.

The condition prevents skin from protecting the body.

Babies with this condition are prone to infections and too much fluid loss, a condition called dehydration.

Hospital care is needed. Medicines and IV fluids can help. Tube feeding may be needed.